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Figure 1: Magnetic resonance imaging of the brain of a child with MELAS syndrome. MRI of the brain axial T2 weighted (A, B) and fluid-attenuated inversion recovery (C, D) sequences showed bilateral (right > left) hyperintense signal changes in the temporal and parieto-occipital gray and white matter with overlying gyral atrophy. Diffusion-weighted (E, F) and corresponding ADC map (G) did not reveal any diffusion restriction. Magnetic resonance spectroscopy (H) lactate peak at 1.3ppm in involved areas (Pos./ppm-1.41)

Figure 1: Magnetic resonance imaging of the brain of a child with MELAS syndrome. MRI of the brain axial T2 weighted (A, B) and fluid-attenuated inversion recovery (C, D) sequences showed bilateral (right > left) hyperintense signal changes in the temporal and parieto-occipital gray and white matter with overlying gyral atrophy. Diffusion-weighted (E, F) and corresponding ADC map (G) did not reveal any diffusion restriction. Magnetic resonance spectroscopy (H) lactate peak at 1.3ppm in involved areas (Pos./ppm-1.41)