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Figure 10: Patient 15. (a and b) Contrast-enhanced CT scan showing a hyperdense lesion with central necrosis and peripheral enhancement in right thalamic region, extending to posterior third ventricular region, medial wall of trigone and splenium of corpus callosum with midline shift and hydrocephalus. (c) H and E stained sections (×200) showing sheets of moderately pleomorphic cells on a fibrillary background along with necrosis. (d) Foci of interspersed endothelial proliferation and mitotic figuresare also noted. The findings are suggestive of a glioblastoma multiforme (WHO grade IV)

Figure 10: Patient 15. (a and b) Contrast-enhanced CT scan showing a hyperdense lesion with central necrosis and peripheral enhancement in right thalamic region, extending to posterior third ventricular region, medial wall of trigone and splenium of corpus callosum with midline shift and hydrocephalus. (c) H and E stained sections (×200) showing sheets of moderately pleomorphic cells on a fibrillary background along with necrosis. (d) Foci of interspersed endothelial proliferation and mitotic figuresare also noted. The findings are suggestive of a <i>glioblastoma multiforme (WHO grade IV)</i>