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Year : 2020  |  Volume : 15  |  Issue : 3  |  Page : 220-223

Urodynamic study findings prior to myelomeningocele repair in neonates

1 Department of Neurosurgery, Florence Nightingale Hospital, Demiroglu Bilim University, Istanbul, Turkey
2 Department of Pediatric Surgery, Medeniyet University, Istanbul, Turkey
3 Department of Neonatology, Istanbul Training and Education Hospital, Istanbul, Turkey

Correspondence Address:
Dr. Huseyin Canaz
Department of Neurosurgery, Florence Nightingale Hospital, Demiroglu Bilim University, Istanbul.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpn.JPN_91_19

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Introduction: Myelomeningocele (MMC) is the most common cause of neurogenic bladder dysfunction in children. Neurogenic bladder dysfunction is developed before birth due to autonomous nervous system affected prenatally in patients with MMC. The aim of this study was to share urodynamic study findings before MMC repair and to discuss the correlation with neurological evaluation. Materials and Methods: We prospectively studied 37 patients who underwent surgery for MMC repair in our institution in the first 20 h of their lives between 2013 and 2016. All patients were evaluated by a neurosurgeon, neonatologist, and pediatric surgeon. Urodynamic study was performed in first 18h of life before MMC repair in all patients. Lesion level, occurrence of hydrocephalus, neurological functions, spinal deformities, and urodynamic study results were analyzed. Results: The study included 18 female and 19 male patients. Overactive detrusor was detected in 22 patients, and hypoactive detrusor was detected in 5 patients. Overactive sphincter muscle was detected in 32 patients, and hypoactive sphincter was detected in 2 patients. Detrusor–sphincter dyssynergia was present in 34 patients. Conclusion: Detailed analysis of urodynamic study findings in larger patient groups may be important to understand the physiopathology of prenatal damage in patients with MMC.


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