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Year : 2018  |  Volume : 13  |  Issue : 4  |  Page : 490-495

Rasmussen’s epileptogenic encephalitis in a tropical country

1 Department of Neurology, Campus University Teaching Hospital, University of Lomé, Lomé, Togo
2 Department of Pediatric Services, Campus University Teaching Hospital, University of Lomé, Lomé, Togo

Correspondence Address:
Prof. Komi Assogba
Department of Neurology, University of Lomé, PO Box: 30284, Lomé
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JPN.JPN_51_18

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Background: Encephalitis of Rasmussen is an inflammatory hemiencephalopathy of unknown etiology. It is a cause of drug-resistant epilepsy. Aim: To report two cases of Rasmussen’s encephalitis (RE) in a low-income setting. Clinical Observation: The cases concerned were that of an 8-year-old boy and a 4-year-old girl. The illness began with daily several seizures at the age of 28 months in the boy and 23 months for the girl. Epileptic seizures were generalized in the elder one and focal in the younger. The elder presented right hemiplegia with severe cognitive impairment. In the younger child, the expression of the language was disturbed, associated with right hemiparesis at 4/5. The electroencephalography recording showed background theta asymmetric rhythm associated with discharges of periodic lateralized epileptiform discharges (PLEDs) into the left hemisphere in the two cases. Brain imaging showed left hemisphere atrophy. The seizures had decreased in intensity after association of several anticonvulsant molecules over a period of 3–6 months. The diagnosis of RE was based on clinical, paraclinical, therapeutic, and evolution arguments. Conclusion: There was a delay to establish the diagnosis. Further studies are needed to evaluate rehabilitation capacities in children with RE before brain maturation.


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