home : about us : ahead of print : current issue : archives search instructions : subscriptionLogin 
Users online: 372      Small font sizeDefault font sizeIncrease font size Print this page Email this page
Year : 2011  |  Volume : 6  |  Issue : 1  |  Page : 65-68

Intraoral plexiform neurofibroma involving the maxilla - pathognomonic of neurofibromatosis type I

Department of Oral Pathology, V. S. Dental College and Hospital, Bangalore, India

Correspondence Address:
Smitha Thammaiah
Department of Oral Pathology, V. S. Dental College and Hospital, Bangalore
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1817-1745.84413

Rights and Permissions

Neurofibromatosis is one of the phakomatosis (neurodermatoses) which are genetically determined hamartomatous or neoplastic diseases of the skin and nervous system. It is not a single entity, but a group of heterogeneous multisystemic neurocutaneous disorders involving both neuroectodermal and mesenchymal derivatives. Plexiform neurofibroma, a histopathologic variant of neurofibroma, is a hallmark of neurofibromatosis type I (NF-I). It is pathognomonic of NF-I and may be the first sign of neurofibromatosis. It often appears within the first 2 years of life or before adolescence and occurs in only 5% of NF-I cases. We present a case of intraosseous plexiform neurofibroma of the maxilla in a 2-year old female, which is rare, along with the oral manifestations and clinicopathological characteristics. Because NF-I is one of the most common genetic disorders and oral manifestations are common, knowledge of the variability of presentation in children is necessary for prompt diagnosis.


Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded169    
    Comments [Add]    

Recommend this journal