| ORIGINAL ARTICLE |
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| Year : 2011 | Volume
: 6
| Issue : 1 | Page : 2-3 |
T-cell epitope finding on EPHA2 for further glioma vaccine development: An immunomics study
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok, India
Correspondence Address:
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok - 10160
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1817-1745.84398
Background: Glioma is a deadly neurological tumor. For modern management of glioma, glioma vaccinotherapy is the new concept. Materials and Methods: Based on present biomedical technique, the identification of T-cell epitopes via MHC mapping can help clarify the inter-relationship of tumor and immune system. This process can be performed using advanced immunoinformatics technique. Results: Here, the author performs an immunoinformatics analysis to find alternative epitopes for glioma-related antigen, EPHA2. Conclusion: After complete manipulation on EPHA2 molecules, the five best epitopes were derived.
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