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Figure 5: Magnetic Resonance images of patients with Menkes disease showing the spectrum of imaging fi ndings: Axial T2-Weighted images of patient 3 (a and b) show the tortuosity of vessels with hyperintense signal changes of white matter with tendency to cyst formation at temporal poles and marked cerebral and cerebellar atrophy. The images of the patient 5 (c and d) shows marked tortuosity of intracranial vascular fl ow voids with mild white matter signal changes and brain atrophy

Figure 5: Magnetic Resonance images of patients with Menkes disease showing the spectrum of imaging fi ndings: Axial T2-Weighted images of patient 3 (a and b) show the tortuosity of vessels with hyperintense signal changes of white matter with tendency to cyst formation at temporal poles and marked cerebral and cerebellar atrophy. The images of the patient 5 (c and d) shows marked tortuosity of intracranial vascular fl ow voids with mild white matter signal changes and brain atrophy