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Figure 4: Magnetic Resonance images of patients with Menkes disease showing the spectrum of imaging fi ndings: Axial T2-Weighted images of the patient 1 at initial presentation (a) and at 5 months follow-up (b) shows tortuous vessels with diffuse white matter signal changes initially progressing to severe brain atrophy with gross bilateral subdural hemorrhages at followup. Patient 6 images (c and d) show marked brain atrophy with bilateral subdural collections

Figure 4: Magnetic Resonance images of patients with Menkes disease showing the spectrum of imaging fi ndings: Axial T2-Weighted images of the patient 1 at initial presentation (a) and at 5 months follow-up (b) shows tortuous vessels with diffuse white matter signal changes initially progressing to severe brain atrophy with gross bilateral subdural hemorrhages at followup. Patient 6 images (c and d) show marked brain atrophy with bilateral subdural collections