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Figure 4: Patient 8. (a) T1 contrast sagittal and (b) T1 contrast axial MR images showing uniform homogenous enhancement in pineal tumor infiltrating third ventricle until foramen of Monro and brain stem. (c) Postoperative T1 sagittal and (d) axial images showing complete tumor removal. (e) H and E (×400) sections showing round to polygonal tumor cells disposed in groups, displaying conspicuous nucleoli at places and variable amount of pale to amphophilic cytoplasm. The groups of tumor cells are separated by fibrous septa infiltrated by small mature lymphocytes. (f) Tumor cells are positive for CD117 (immunohistochemical stain; ×400). (g) Tumor cells are positive for placenta-like alkaline phosphatase (PLAP) (immunohistochemical stain; ×400). The histopathology and immunohistochemistry confirm the presence of a germinoma

Figure 4: Patient 8. (a) T1 contrast sagittal and (b) T1 contrast axial MR images showing uniform homogenous enhancement in pineal tumor infiltrating third ventricle until foramen of Monro and brain stem. (c) Postoperative T1 sagittal and (d) axial images showing complete tumor removal. (e) H and E (×400) sections showing round to polygonal tumor cells disposed in groups, displaying conspicuous nucleoli at places and variable amount of pale to amphophilic cytoplasm. The groups of tumor cells are separated by fibrous septa infiltrated by small mature lymphocytes. (f) Tumor cells are positive for CD117 (immunohistochemical stain; ×400). (g) Tumor cells are positive for placenta-like alkaline phosphatase (PLAP) (immunohistochemical stain; ×400). The histopathology and immunohistochemistry confirm the presence of a <i>germinoma</i>