Journal of Pediatric Neurosciences
: 2019  |  Volume : 14  |  Issue : 3  |  Page : 177-

Diphtheritic polyneuropathy

Beuy Joob1, Viroj Wiwanitkit2,  
1 Medical Center, Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Department of Tropical Medicine, Hainan Medical University, Haiko, China; Department of Community Medicine, Dr. D. Y. Patil University, Pune, Maharashtra, India; Department of Biological Science, Joseph Ayo Babalola University, Ilesa, Osun State, Nigeria; Departmnet of Medical Science, Faculty of Medicine, University of Niš, Niš, Serbia

Correspondence Address:
Dr. Beuy Joob
Medical Center, Sanitation 1 Medical Academic Center, Bangkok

How to cite this article:
Joob B, Wiwanitkit V. Diphtheritic polyneuropathy.J Pediatr Neurosci 2019;14:177-177

How to cite this URL:
Joob B, Wiwanitkit V. Diphtheritic polyneuropathy. J Pediatr Neurosci [serial online] 2019 [cited 2020 May 30 ];14:177-177
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Dear Editor,

The report on “prospective study of diphtheria for neurological complications” is very interesting.[1] Prasad and Rai reported 28 cases and they noted complete recovery in all the cases.[1] They concluded that “pediatricians/neurophysicians should have a high index of suspicion to recognize diphtheritic polyneuropathy.[1]” Indeed, the neurological complication is not uncommon in diphtheria. In a report, 10% of the cases presented had the neurological complication.[2] We would like to share idea and experience on this issue. In our country, Thailand, there are sporadic outbreaks of diphtheria. In a recent outbreak in a province in Thailand, no neurological complication was reported but the common complication observed was cardiac complication.[3] Nevertheless, there is also an interesting report from our setting on deadly neurological complication due to diphtheritic subacute infective endocarditis.[4] In that case, the patient developed convulsion, resulting in brain death.[4] This implies the need for close observation on the complications, either neurological complication or not, in the patients with diphtheria. The neurological complication might be primary or secondary, and the complication might be finally recovered, as reported by Prasad and Rai,[1] or might result in fatality.


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1Prasad PL, Rai PL. Prospective study of diphtheria for neurological complications. J Pediatr Neurosci 2018;13:313-6.
2Jain A, Samdani S, Meena V, Sharma MP. Diphtheria: it is still prevalent!!! Int J Pediatr Otorhinolaryngol 2016;86:68-71.
3Pantukosit P, Arpornsuwan M, Sookananta K. A diphtheria outbreak in Buri Ram, Thailand. Southeast Asian J Trop Med Public Health 2008;39:690-6.
4Lolekha R, Supradish P, Kirawittaya T, Srimaharaja S, Chotpitayasunondh T. Subacute infective endocarditis caused by Corynebacterium diphtheriae: a case report. J Med Assoc Thai 2003;86:S696-700.