Journal of Pediatric Neurosciences
: 2015  |  Volume : 10  |  Issue : 4  |  Page : 379--381

Pediatric gliomatosis cerebri mimicking tubercular encephalitis

Namit Singhal1, Vinay Agarwal2 
1 Department of Neurosciences, SS Hospital, Agra, Uttar Pradesh, India
2 Agarwal Neurology Clinic, Agra, Uttar Pradesh, India

Correspondence Address:
Namit Singhal
SS Hospital, Hari Parwat Crossing, Agra - 282 003, Uttar Pradesh

Gliomatosis cerebri (GC) is a diffuse infiltrating glial neoplasm of astrocytic origin. GC in children is rare and difficult to diagnose, often presenting with a variety of signs and symptoms that may mimic myriad conditions. We discuss here the presentation and diagnosis of GC in a child who was initially treated on lines of tubercular encephalitis, with transient clinical relief and disappearance of enhancing component of the disease on magnetic resonance imaging. In this report, we highlight the limitations of clinical presentation and neuroimaging as well as the essential role of histological evaluation for the diagnosis of GC in children. Also is highlighted a more benign and protracted clinical course following radiotherapy in a subset of patients, with Ki index <10%, thereby stressing earliest possible diagnosis. A new prognostic classification can also be proposed for pediatric GC based on various parameters. Since these are rare cases, a combined effort is required for this.

How to cite this article:
Singhal N, Agarwal V. Pediatric gliomatosis cerebri mimicking tubercular encephalitis.J Pediatr Neurosci 2015;10:379-381

How to cite this URL:
Singhal N, Agarwal V. Pediatric gliomatosis cerebri mimicking tubercular encephalitis. J Pediatr Neurosci [serial online] 2015 [cited 2020 Jul 2 ];10:379-381
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