Journal of Pediatric Neurosciences
CASE REPORT
Year
: 2013  |  Volume : 8  |  Issue : 2  |  Page : 141--145

Neuropsychological impairment in early-onset hydrocephalus and epilepsy with continuous spike-waves during slow-wave sleep: A case report and literature review


Annio Posar1, Antonia Parmeggiani2 
1 Child Neurology and Psychiatry Unit, IRCCS Institute of Neurological Sciences of Bologna, Bologna; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy
2 Child Neurology and Psychiatry Unit, IRCCS Institute of Neurological Sciences of Bologna, Bologna; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy

Correspondence Address:
Annio Posar
Child Neurology and Psychiatry Unit, IRCCS Institute of Neurological Sciences of Bologna, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Altura 3, 40139 Bologna
Italy

Epilepsy with continuous spike-waves during slow-wave sleep (CSWS) is often characterized by a severe cognitive and behavioral impairment. Symptomatic cases also include patients with an early-onset hydrocephalus, but in literature detailed neuropsychological data on these subjects are not available. We describe the results of serial cognitive assessments in a girl with shunted early-onset hydrocephalus, followed by partial epilepsy complicated with CSWS at 4 years 10 months, in which a dramatic cognitive and behavioral deterioration occurred few months after CSWS onset. Adrenocorticotropic hormone treatment improved both clinical and electroencephalogram picture, but an impairment of visual perception, visual-motor coordination and executive functions persisted after CSWS disappearance. We hypothesize, in this case, an involvement of right occipital-parietal lobe and prefrontal lobe.


How to cite this article:
Posar A, Parmeggiani A. Neuropsychological impairment in early-onset hydrocephalus and epilepsy with continuous spike-waves during slow-wave sleep: A case report and literature review.J Pediatr Neurosci 2013;8:141-145


How to cite this URL:
Posar A, Parmeggiani A. Neuropsychological impairment in early-onset hydrocephalus and epilepsy with continuous spike-waves during slow-wave sleep: A case report and literature review. J Pediatr Neurosci [serial online] 2013 [cited 2019 Sep 19 ];8:141-145
Available from: http://www.pediatricneurosciences.com/article.asp?issn=1817-1745;year=2013;volume=8;issue=2;spage=141;epage=145;aulast=Posar;type=0