| ORIGINAL ARTICLE
|Year : 2020 | Volume
| Issue : 2 | Page : 99-104
Increased hemoglobin and plateletcrit levels indicating hemoconcentration in pediatric patients with migraine
Sevim Sahin1, Betul Diler Durgut2, Beril Dilber1, Elif Acar Arslan1, Tulay Kamasak1, Ali Cansu1
1 Division of Pediatric Neurology, Department of Pediatrics, School of Medicine, Karadeniz Technical University, Trabzone, Turkey
2 Division of Pediatric Neurology, Maternity and Children Diseases Education and Research Hospital, Giresun University, Giresun, Turkey
Introduction: Fluid intake was reported to reduce migraine attacks. This may be due to its effect on hemoconcentration. Hemoconcentration may manifest itself by increasing in the hemoglobin and platelet-related values. This study aimed to reveal hemoconcentration by evaluating complete blood cell counts in attack-free periods of pediatric patients with migraine. Materials and Methods: Consecutive children with migraine (n = 70) and tension-type headache (TTH) (n = 65) were compared with the control groups. Control 1 (n = 70) and control 2 (n = 60) groups consisted of age- and gender-matched patients, respectively. Control 2 group patients had gastrointestinal symptoms leading to fluid loss, which may have caused hemoconcentration. To evaluate hemoglobin and platelets together, the M1-value was created by multiplying hemoglobin level by plateletcrit. Results: The M1-value was higher in the migraine group than in control 1 and TTH groups (P = 0.017 and 0.034) and the hemoglobin and hematocrit levels were also higher in the migraine group than in control 2 group (P = 0.013 and 0.012). Female patients with migraine had higher hemoglobin levels as compared to the female patients in control group 1 (P = 0.041). Male patients with migraine had higher M1-values than the male patients in control group 1 (P = 0.034). In the subgroup of migraine with aura (n = 10), folic acid was significantly lower than the other patients with migraine (P = 0.02). Conclusion: This study suggests that migraine may be accompanied with hemoconcentration in children.
Dr. Sevim Sahin
Division of Pediatric Neurology, Department of Pediatrics, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon.
Source of Support: None, Conflict of Interest: None
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