home : about us : ahead of print : current issue : archives search instructions : subscriptionLogin 
Users online: 1158      Small font sizeDefault font sizeIncrease font size Print this page Email this page
 CASE REPORT
Year : 2020  |  Volume : 15  |  Issue : 2  |  Page : 153-156

A rare case of peripheral nerve hyperexcitability in childhood: Isaacs syndrome


1 Department of Pediatrics, Division of Child Neurology, Ege University Medical Faculty, Izmir, Turkey
2 Department of Pediatrics, Ege University Medical Faculty, Izmir, Turkey
3 Department of Neurology, Ege University Medical Faculty, Izmir, Turkey

Correspondence Address:
Prof. Hasan Tekgul
Division of Pediatric Neurology, Department of Pediatrics, Ege University Medical School, Izmir.
Turkey
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpn.JPN_128_19

Rights and Permissions

Isaacs syndrome is rare disorder with peripheral nerve hyperexcitability syndromes with acquired neuromyotonia in childhood. We present a 13-year-old girl with muscle stiffness and neuromyotonia diagnosed Isaac syndrome with spontaneous discharge potentials on motor unit in electromyography and the diagnosis supported by the presence of antinuclear antibodies. A successful treatment was obtained using low-dose carbamazepine. Cause of Isaacs syndrome is unknown, generally thought to be an autoimmune etiology with voltage-gated potassium channelopathy; it sometimes occurs as a paraneoplastic syndrome. Early use of electromyography has critical role in the differential diagnosis with certain muscle disorders and peripheral nerve hyperexcitability syndromes.






[FULL TEXT] [PDF]*


        
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed237    
    Printed18    
    Emailed0    
    PDF Downloaded18    
    Comments [Add]    

Recommend this journal