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Year : 2019  |  Volume : 14  |  Issue : 4  |  Page : 225-227

Unilateral open-lip schizencephaly with tonsillar herniation in a preterm infant

1 Department of Pediatrics, University of South Alabama, Mobile, Alabama, USA
2 Department of Pediatric Neurosurgery, University of South Alabama, Mobile, Alabama, USA
3 Department of Obstetrics and Gynecology, Maternal-Fetal Medicine Division, University of South Alabama, Mobile, Alabama, USA
4 Department of Pediatrics, Neonatology Division, University of South Alabama, Mobile, Alabama, USA

Correspondence Address:
Dr. Ramachandra Bhat
1700 Center Street, Mobile, Alabama, 36604.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpn.JPN_75_19

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Schizencephaly is a rare type of neuronal migration disorder characterized by the presence of a cerebral hemispheric cleft that extends from lateral ventricles to the cortical surface of the brain. We report a rare case of prenatally diagnosed unilateral schizencephaly in a late preterm infant who manifested with rapidly progressive hydrocephalus with massive enlargement of posterior cerebrospinal fluid spaces with tonsillar herniation that was successfully treated with placement of a ventriculoperitoneal shunt.


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