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 CASE REPORT
Year : 2013  |  Volume : 8  |  Issue : 2  |  Page : 150-153

Acute longitudinal myelitis as the first presentation in child with systemic lupus erythematosus


1 Department of Paediatric Rheumatology, Children's Hospital, Leicester Royal Infirmary, University Hospitals of Leicester, Leicester, United Kingdom
2 Department of Paediatric Neurology, Children's Hospital, Leicester Royal Infirmary, University Hospitals of Leicester, Leicester, United Kingdom

Correspondence Address:
Arani V Sridhar
Children's Hospital, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester - LE1 5WW
United Kingdom
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1817-1745.117854

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Systemic lupus erythematosus (SLE) is a multi-system auto-immune disorder that is characterized by widespread immune dysregulation, formation of auto-antibodies, and immune complexes, resulting in inflammation and potential damage to variety of organs. It is complicated by neurological manifestations in 25-95% of the patients. Acute transverse myelitis (ATM) may be a complication in 1-2% of patients with SLE but in some patients it may be the initial manifestation of SLE. This sub-group of patients where ATM is the presenting feature may not fulfil the ACR criteria for the diagnosis of SLE which may delay the diagnosis and may affect the outcome. In those patients where the involvement is more than four segments of the spine are believed to have poor prognosis, but early diagnosis and treatment may alter the course and lead to a better outcome. We describe a young Polish girl where ATM was the initial manifestation of SLE involving almost the whole length of spine but she had a reasonably good outcome following early diagnosis and aggressive treatment.






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