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 CASE REPORT
Year : 2012  |  Volume : 7  |  Issue : 3  |  Page : 218-220

Sacrococcygeal myxopapillary ependymoma with anaplastic ependymoma component in an infant


1 Department of Pathology, Kasturba Medical College, Karnataka, India
2 Department of Paediatric Surgery, Kasturba Medical College, Karnataka, India
3 Department of Radiology, K. S. Hegde Medical Academy, Mangalore, Karnataka, India

Correspondence Address:
Shrijeet Chakraborti
Department of Pathology, Kasturba Medical College - Mangalore, Lighthouse Hill Road, Mangalore - 575 001, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1817-1745.106485

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Sacrococcygeal location of myxopapillary ependymoma (MPE) is uncommon. Local recurrence and metastases are on record inspite of its benign characteristics. We report a rare case of sacrococcygeal MPE in an 11-month-old female child who showed typical myxopapillary ependymal histology along with anaplastic ependymal component. Ki-67 labeling index in the myxopapillary component was 4-5% and in the anaplastic component was 70%. Six weeks after gross total resection of the tumor, the child presented with local recurrence and metastasis in the right inguinal lymph nodes and was treated with chemotherapy. The present case of sacrococcygeal MPE with anaplastic ependymoma component is the second case on record in the medical literature, and the first case without any syndromic features. Metastasis in this case can be explained because of the anaplastic component, with mitotic count of 5-6/high power field and high Ki-67 labeling index.






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