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 CASE REPORT
Year : 2012  |  Volume : 7  |  Issue : 2  |  Page : 117-119

Infantile Alexander disease: A rare leukodystrophy


1 Department of Pediatrics, JSS Medical College, JSS University, Mysore, Karnataka, India
2 Department of Neurology, JSS Medical College, JSS University, Mysore, Karnataka, India

Correspondence Address:
K Jagadish Kumar
Department of Pediatrics, JSS Medical College, Mysore, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1817-1745.102573

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Infantile Alexander disease (AD) is a rare leukodystrophy characterized by its early onset within 2 years of life and clinically presents with macrocephaly, seizures, and retarded psychomotor development. Magnetic resonance imaging (MRI) shows characteristic symmetric white matter abnormalities with frontal predominance. We present a case of infantile AD with typical clinical characteristics and MRI features.






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