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 NEUROIMAGING
Year : 2012  |  Volume : 7  |  Issue : 1  |  Page : 27-29

Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration


Department of Radiodiagnosis, Dayanand Medical College and Hospital, Ludhiana, Punjab, India

Correspondence Address:
Paramdeep Singh
Department of Radiodiagnosis, Dayanand Medical College and Hospital, Ludhiana, Punjab
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1817-1745.97618

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Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia. On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus. This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance.






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