home : about us : ahead of print : current issue : archives search instructions : subscriptionLogin 
Users online: 532      Small font sizeDefault font sizeIncrease font size Print this page Email this page
 CASE REPORT
Year : 2011  |  Volume : 6  |  Issue : 2  |  Page : 146-148

Striatal necrosis in type 1 glutaric aciduria: Different stages in two siblings


1 Department of Radiodiagnosis, Devi Scans, Medical College PO, Thiruvananthapuram, Kerala, India
2 Department of Radiodiagnosis, Kerala Institute of Medical Sciences, Thiruvananthapuram, Kerala, India

Correspondence Address:
Anitha Sen
Department of Radiodiagnosis, Devi Scans, Medical College PO, Thiruvananthapuram - 695 011, Kerala
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1817-1745.92845

Rights and Permissions

Two siblings born of a consanguineous marriage with history of neurologic deterioration were imaged. Imaging features are classical of glutaric aciduria type 1 (GA-1), acute (striatal necrosis) stage in younger sibling, and chronic stage in older sibling. GA-1 is an autosomal recessive disease with typical imaging features. Greater awareness about this condition among clinicians and radiologists is essential for early diagnosis and prevention of its catastrophic consequences. Striatal necrosis with stroke-like signal intensity on imaging correlates with clinical stage of patients.






[FULL TEXT] [PDF]*


        
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed4015    
    Printed87    
    Emailed1    
    PDF Downloaded131    
    Comments [Add]    

Recommend this journal